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25 //
26 //
27 // D Chiappara, GAP Cirrone, G Petringa
28 //
29 // ** RADIOBIO example **
30 // make easy the calculation of the main radiobiology quantities used in
31 // charged particles radiation therapy: depth dose, Fluence in depth,
32 // LET (Linear Energy Transfer) and RBE (Relative Bioology Effectiveness)
33 //
34
35 #include "G4PhysListFactory.hh"
36 #include "G4RunManagerFactory.hh"
37 #include "G4ScoringManager.hh"
38 #include "G4Timer.hh"
39 #include "G4UImanager.hh"
40 #include "G4UImessenger.hh"
41 #include "G4VModularPhysicsList.hh"
42 #include "Randomize.hh"
43 #include "globals.hh"
44
45 #include "ActionInitialization.hh"
46 #include "DetectorConstruction.hh"
47 #include "Dose.hh"
48 #include "LET.hh"
49 #include "Manager.hh"
50 #include "PhysicsList.hh"
51 #include "PrimaryGeneratorAction.hh"
52 #include "RBE.hh"
53 #include <time.h>
54
55 // #ifdef G4VIS_USE
56 #include "G4VisExecutive.hh"
57 // #endif
58
59 // #ifdef G4UI_USE
60 #include "G4UIExecutive.hh"
61 // #endif
62
63 using namespace RadioBio;
64
65 ////////////////////////////////////////////////////////////////////////////////
66 int main(int argc, char** argv)
67 {
68 G4UIExecutive* ui = nullptr;
69 if (argc == 1) {
70 ui = new G4UIExecutive(argc, argv);
71 }
72
73 // Instantiate the G4Timer object, to monitor the CPU time spent for
74 // the entire execution
75 G4Timer* theTimer = new G4Timer();
76 // Start the benchmark
77 theTimer->Start();
78
79 // Set the Random engine
80 // The following guarantees random generation also for different runs
81 // in multithread
82 CLHEP::RanluxEngine defaultEngine(1234567, 4);
83 G4Random::setTheEngine(&defaultEngine);
84 G4int seed = time(NULL);
85 G4Random::setTheSeed(seed);
86
87 // Create the run manager. Uses by default serial or parallel computation.
88 auto* runManager = G4RunManagerFactory::CreateRunManager(G4RunManagerType::Default);
89
90 // Create Scoring manager
91 G4ScoringManager* scoringManager = G4ScoringManager::GetScoringManager();
92 scoringManager->SetVerboseLevel(1);
93
94 // Creating PhysicsList
95 G4VModularPhysicsList* phys = new PhysicsList();
96
97 // Set mandatory initialization classes
98 DetectorConstruction* det = new DetectorConstruction();
99 runManager->SetUserInitialization(det);
100
101 // Creation of Manager
102 Manager* RBman = Manager::CreateInstance();
103
104 // Create and Register Radiobiological quantities
105 Dose* dose = new Dose();
106 RBman->Register(dose, "Dose");
107
108 LET* let = new LET();
109 RBman->Register(let, "LET");
110
111 RBE* rbe = new RBE();
112 RBman->Register(rbe, "RBE");
113
114 // Initialisation of physics
115 runManager->SetUserInitialization(phys);
116
117 // Initialisation of the Actions
118 runManager->SetUserInitialization(new ActionInitialization(det));
119
120 // Initialize command based scoring
121 G4ScoringManager::GetScoringManager();
122
123 // Initialise the Visualisation
124 // #ifdef G4VIS_USE
125 G4VisManager* visManager = new G4VisExecutive;
126 visManager->Initialize();
127 // #endif
128
129 //** Get the pointer to the User Interface manager
130 G4UImanager* UImanager = G4UImanager::GetUIpointer();
131
132 if (!ui) {
133 // batch mode
134 G4String command = "/control/execute ";
135 G4String fileName = argv[1];
136 UImanager->ApplyCommand(command + fileName);
137 }
138
139 else {
140 // UImanager -> ApplyCommand("/control/execute macro/MacroPablo.mac");
141 UImanager->ApplyCommand("/control/execute macro/visualize.mac");
142
143 ui->SessionStart();
144 delete ui;
145 }
146
147 // Save data in RadioBioManager
148 RBman->StoreAll();
149
150 // Stop the benchmark here
151 theTimer->Stop();
152
153 G4cout << "The simulation took: " << theTimer->GetRealElapsed() << " s to run (real time)"
154 << G4endl;
155
156 delete theTimer;
157 delete runManager;
158 }
159