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Geant4/examples/advanced/dna/dsbandrepair/analysis/include/AnalysisHandler.hh

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  1 //
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 26 //
 27 //
 28 /// \file AnalysisHandler.hh
 29 /// \brief Definition of the AnalysisHandler class
 30 
 31 #ifndef AnalysisHandler_h
 32 #define AnalysisHandler_h 1
 33 
 34 #include <memory>
 35 #include "ScanDamage.hh"
 36 #include "TLKModel.hh"
 37 #include "LEMIVModel.hh"
 38 #include "BelovModel.hh"
 39 
 40 class AnalysisHandler
 41 {
 42     public:
 43     AnalysisHandler(/* args */);
 44     ~AnalysisHandler() = default;
 45     void SetThresholdEnergy(double e);
 46     void GetAllDamageAndScanSB();
 47     void GiveMeSBs();
 48     void ApplyDNAModel(const std::string dnamodel);
 49     void SetBpForDSB(unsigned int pVal);
 50     void SetParametersForTLKModel(double pLambda1 = 3.0,double pLambda2=0.03, 
 51                                     double pBeta1=0.01, double pBeta2=0.06,double pEta=0.002);
 52     void SetParametersForLEMIVModel(double pLoopLength=2e6,double pFunrej=0,
 53                                     double pTfast=0.24,double pTslow=2.81);
 54     void CreateSDD(std::string filename);
 55 private:
 56     ///void GetDoseFromEdep();
 57     std::unique_ptr<ScanDamage> fScanDamage;
 58     std::unique_ptr<TLKModel> fTLKModel;
 59     std::unique_ptr<LEMIVModel> fLEMIVModel;
 60     std::unique_ptr<BelovModel> fBelovModel;
 61     std::vector<Damage> fAllDamage;
 62     
 63     std::pair<float,float> fNsDSBandError = {0,0};
 64     std::pair<float,float> fNcDSBandError = {0,0};
 65     std::pair<float,float> fNDSBandError = {0,0};
 66     std::pair<float,float> fNDSBdirandError = {0,0}; // DSB has contribution from at least one direct  damage
 67     std::pair<float,float> fNDSBIndandError = {0,0}; // DSB has contribution from at least one indirect  damage
 68     std::pair<float,float> fNDSBdirIandError = {0,0}; // DSB has contribution from both direct and indirect damage
 69     std::pair<float,float> fNSSBandError = {0,0};
 70     std::pair<float,float> fNSBandError = {0,0};
 71     std::pair<float,float> fNdirSBandError = {0,0};
 72     std::pair<float,float> fNindirSBandError = {0,0};
 73 
 74     bool fIsSBScanned = false;
 75     // num of bp to consider a DSB for the MakeCluster function
 76   // default value is 10
 77   unsigned int fBpForDSB{10};
 78     // store dose deposited in nucleus cell
 79   double fDose{0};
 80     //TLK: Compute a SF Curve
 81     double pTLKDoseMax{0}, pTLKDeltaDose{0};
 82     //LEMIV: compute fraction of unrejoined DSB up to pLEMIVTimeMax (h) and  pLEMIVDeltaTime steps
 83     double pLEMIVtimeMax{0}, pLEMIVdeltaTime{0};
 84 
 85     double fNBp{0};// number of base pairs
 86     double fEdepInNucleus{0}; // eV
 87     double fNucleusVolume{0};
 88 
 89     std::map<int,unsigned long long int> fChromosomeBpMap; //Store number of Bp in each Chomosomes;
 90 };
 91 
 92 #endif
 93