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25 // 25 //
26 // 26 //
27 // D Chiappara, GAP Cirrone, G Petringa 27 // D Chiappara, GAP Cirrone, G Petringa
28 // 28 //
29 // ** RADIOBIO example ** 29 // ** RADIOBIO example **
30 // make easy the calculation of the main radio 30 // make easy the calculation of the main radiobiology quantities used in
31 // charged particles radiation therapy: depth 31 // charged particles radiation therapy: depth dose, Fluence in depth,
32 // LET (Linear Energy Transfer) and RBE (Relat 32 // LET (Linear Energy Transfer) and RBE (Relative Bioology Effectiveness)
33 // 33 //
34 34
35 #include "G4PhysListFactory.hh" 35 #include "G4PhysListFactory.hh"
36 #include "G4RunManagerFactory.hh" 36 #include "G4RunManagerFactory.hh"
37 #include "G4ScoringManager.hh" 37 #include "G4ScoringManager.hh"
38 #include "G4Timer.hh" 38 #include "G4Timer.hh"
39 #include "G4UImanager.hh" 39 #include "G4UImanager.hh"
40 #include "G4UImessenger.hh" 40 #include "G4UImessenger.hh"
41 #include "G4VModularPhysicsList.hh" 41 #include "G4VModularPhysicsList.hh"
42 #include "Randomize.hh" 42 #include "Randomize.hh"
43 #include "globals.hh" 43 #include "globals.hh"
44 44
45 #include "ActionInitialization.hh" 45 #include "ActionInitialization.hh"
46 #include "DetectorConstruction.hh" 46 #include "DetectorConstruction.hh"
47 #include "Dose.hh" 47 #include "Dose.hh"
48 #include "LET.hh" 48 #include "LET.hh"
49 #include "Manager.hh" 49 #include "Manager.hh"
50 #include "PhysicsList.hh" 50 #include "PhysicsList.hh"
51 #include "PrimaryGeneratorAction.hh" 51 #include "PrimaryGeneratorAction.hh"
52 #include "RBE.hh" 52 #include "RBE.hh"
53 #include <time.h> 53 #include <time.h>
54 54
55 // #ifdef G4VIS_USE << 55 //#ifdef G4VIS_USE
56 #include "G4VisExecutive.hh" 56 #include "G4VisExecutive.hh"
57 // #endif << 57 //#endif
58 58
59 // #ifdef G4UI_USE << 59 //#ifdef G4UI_USE
60 #include "G4UIExecutive.hh" 60 #include "G4UIExecutive.hh"
61 // #endif << 61 //#endif
62 62
63 using namespace RadioBio; 63 using namespace RadioBio;
64 64
65 ////////////////////////////////////////////// 65 ////////////////////////////////////////////////////////////////////////////////
66 int main(int argc, char** argv) 66 int main(int argc, char** argv)
67 { 67 {
68 G4UIExecutive* ui = nullptr; 68 G4UIExecutive* ui = nullptr;
69 if (argc == 1) { 69 if (argc == 1) {
70 ui = new G4UIExecutive(argc, argv); 70 ui = new G4UIExecutive(argc, argv);
71 } 71 }
72 72
73 // Instantiate the G4Timer object, to monito 73 // Instantiate the G4Timer object, to monitor the CPU time spent for
74 // the entire execution 74 // the entire execution
75 G4Timer* theTimer = new G4Timer(); 75 G4Timer* theTimer = new G4Timer();
76 // Start the benchmark 76 // Start the benchmark
77 theTimer->Start(); 77 theTimer->Start();
78 78
79 // Set the Random engine 79 // Set the Random engine
80 // The following guarantees random generatio 80 // The following guarantees random generation also for different runs
81 // in multithread 81 // in multithread
82 CLHEP::RanluxEngine defaultEngine(1234567, 4 82 CLHEP::RanluxEngine defaultEngine(1234567, 4);
83 G4Random::setTheEngine(&defaultEngine); 83 G4Random::setTheEngine(&defaultEngine);
84 G4int seed = time(NULL); 84 G4int seed = time(NULL);
85 G4Random::setTheSeed(seed); 85 G4Random::setTheSeed(seed);
86 86
87 // Create the run manager. Uses by default s 87 // Create the run manager. Uses by default serial or parallel computation.
88 auto* runManager = G4RunManagerFactory::Crea 88 auto* runManager = G4RunManagerFactory::CreateRunManager(G4RunManagerType::Default);
89 89
90 // Create Scoring manager 90 // Create Scoring manager
91 G4ScoringManager* scoringManager = G4Scoring 91 G4ScoringManager* scoringManager = G4ScoringManager::GetScoringManager();
92 scoringManager->SetVerboseLevel(1); 92 scoringManager->SetVerboseLevel(1);
93 93
94 // Creating PhysicsList 94 // Creating PhysicsList
95 G4VModularPhysicsList* phys = new PhysicsLis 95 G4VModularPhysicsList* phys = new PhysicsList();
96 96
97 // Set mandatory initialization classes 97 // Set mandatory initialization classes
98 DetectorConstruction* det = new DetectorCons 98 DetectorConstruction* det = new DetectorConstruction();
99 runManager->SetUserInitialization(det); 99 runManager->SetUserInitialization(det);
100 100
101 // Creation of Manager 101 // Creation of Manager
102 Manager* RBman = Manager::CreateInstance(); 102 Manager* RBman = Manager::CreateInstance();
103 103
104 // Create and Register Radiobiological quant 104 // Create and Register Radiobiological quantities
105 Dose* dose = new Dose(); 105 Dose* dose = new Dose();
106 RBman->Register(dose, "Dose"); 106 RBman->Register(dose, "Dose");
107 107
108 LET* let = new LET(); 108 LET* let = new LET();
109 RBman->Register(let, "LET"); 109 RBman->Register(let, "LET");
110 110
111 RBE* rbe = new RBE(); 111 RBE* rbe = new RBE();
112 RBman->Register(rbe, "RBE"); 112 RBman->Register(rbe, "RBE");
113 113
114 // Initialisation of physics 114 // Initialisation of physics
115 runManager->SetUserInitialization(phys); 115 runManager->SetUserInitialization(phys);
116 116
117 // Initialisation of the Actions 117 // Initialisation of the Actions
118 runManager->SetUserInitialization(new Action 118 runManager->SetUserInitialization(new ActionInitialization(det));
119 119
120 // Initialize command based scoring 120 // Initialize command based scoring
121 G4ScoringManager::GetScoringManager(); 121 G4ScoringManager::GetScoringManager();
122 122
123 // Initialise the Visualisation 123 // Initialise the Visualisation
124 // #ifdef G4VIS_USE << 124 //#ifdef G4VIS_USE
125 G4VisManager* visManager = new G4VisExecutiv 125 G4VisManager* visManager = new G4VisExecutive;
126 visManager->Initialize(); 126 visManager->Initialize();
127 // #endif << 127 //#endif
128 128
129 //** Get the pointer to the User Interface m 129 //** Get the pointer to the User Interface manager
130 G4UImanager* UImanager = G4UImanager::GetUIp 130 G4UImanager* UImanager = G4UImanager::GetUIpointer();
131 131
132 if (!ui) { 132 if (!ui) {
133 // batch mode 133 // batch mode
134 G4String command = "/control/execute "; 134 G4String command = "/control/execute ";
135 G4String fileName = argv[1]; 135 G4String fileName = argv[1];
136 UImanager->ApplyCommand(command + fileName 136 UImanager->ApplyCommand(command + fileName);
137 } 137 }
138 138
139 else { 139 else {
140 // UImanager -> ApplyCommand("/control/exe 140 // UImanager -> ApplyCommand("/control/execute macro/MacroPablo.mac");
141 UImanager->ApplyCommand("/control/execute 141 UImanager->ApplyCommand("/control/execute macro/visualize.mac");
142 142
143 ui->SessionStart(); 143 ui->SessionStart();
144 delete ui; 144 delete ui;
145 } 145 }
146 146
147 // Save data in RadioBioManager 147 // Save data in RadioBioManager
148 RBman->StoreAll(); 148 RBman->StoreAll();
149 149
150 // Stop the benchmark here 150 // Stop the benchmark here
151 theTimer->Stop(); 151 theTimer->Stop();
152 152
153 G4cout << "The simulation took: " << theTime 153 G4cout << "The simulation took: " << theTimer->GetRealElapsed() << " s to run (real time)"
154 << G4endl; 154 << G4endl;
155 155
156 delete theTimer; 156 delete theTimer;
157 delete runManager; 157 delete runManager;
158 } 158 }
159 159