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Geant4/examples/extended/medical/dna/pdb4dna/src/EventAction.cc

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  1 //
  2 // ********************************************************************
  3 // * License and Disclaimer                                           *
  4 // *                                                                  *
  5 // * The  Geant4 software  is  copyright of the Copyright Holders  of *
  6 // * the Geant4 Collaboration.  It is provided  under  the terms  and *
  7 // * conditions of the Geant4 Software License,  included in the file *
  8 // * LICENSE and available at  http://cern.ch/geant4/license .  These *
  9 // * include a list of copyright holders.                             *
 10 // *                                                                  *
 11 // * Neither the authors of this software system, nor their employing *
 12 // * institutes,nor the agencies providing financial support for this *
 13 // * work  make  any representation or  warranty, express or implied, *
 14 // * regarding  this  software system or assume any liability for its *
 15 // * use.  Please see the license in the file  LICENSE  and URL above *
 16 // * for the full disclaimer and the limitation of liability.         *
 17 // *                                                                  *
 18 // * This  code  implementation is the result of  the  scientific and *
 19 // * technical work of the GEANT4 collaboration.                      *
 20 // * By using,  copying,  modifying or  distributing the software (or *
 21 // * any work based  on the software)  you  agree  to acknowledge its *
 22 // * use  in  resulting  scientific  publications,  and indicate your *
 23 // * acceptance of all terms of the Geant4 Software license.          *
 24 // ********************************************************************
 25 //
 26 // This example is provided by the Geant4-DNA collaboration
 27 // Any report or published results obtained using the Geant4-DNA software
 28 // shall cite the following Geant4-DNA collaboration publication:
 29 // Med. Phys. 37 (2010) 4692-4708
 30 // Delage et al. PDB4DNA: implementation of DNA geometry from the Protein Data
 31 //                  Bank (PDB) description for Geant4-DNA Monte-Carlo
 32 //                  simulations (submitted to Comput. Phys. Commun.)
 33 // The Geant4-DNA web site is available at http://geant4-dna.org
 34 //
 35 //
 36 /// \file EventAction.cc
 37 /// \brief Implementation of the EventAction class
 38 
 39 #include "EventAction.hh"
 40 
 41 #include "EventActionMessenger.hh"
 42 
 43 #include "G4AnalysisManager.hh"
 44 #include "G4Event.hh"
 45 #include "G4SystemOfUnits.hh"
 46 #include "G4UnitsTable.hh"
 47 #include "Randomize.hh"
 48 
 49 #include <algorithm>
 50 
 51 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
 52 
 53 EventAction::EventAction() : G4UserEventAction()
 54 {
 55   // default parameter values
 56   //
 57   fThresEdepForSSB = 8.22 * eV;
 58   fThresDistForDSB = 10;
 59   fTotalEnergyDeposit = 0;
 60 
 61   // create commands
 62   //
 63   fpEventMessenger = new EventActionMessenger(this);
 64 }
 65 
 66 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
 67 
 68 EventAction::~EventAction()
 69 {
 70   delete fpEventMessenger;
 71 }
 72 
 73 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
 74 
 75 void EventAction::BeginOfEventAction(const G4Event*)
 76 {
 77   // Initialization of parameters
 78   //
 79   fTotalEnergyDeposit = 0.;
 80   fEdepStrand1.clear();
 81   fEdepStrand2.clear();
 82 }
 83 
 84 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
 85 
 86 void EventAction::EndOfEventAction(const G4Event*)
 87 {
 88   // At the end of an event, compute the number of strand breaks
 89   //
 90   G4int sb[2] = {0, 0};
 91   ComputeStrandBreaks(sb);
 92   // Fill histograms
 93   //
 94   G4AnalysisManager* analysisManager = G4AnalysisManager::Instance();
 95 
 96   if (fTotalEnergyDeposit > 0.) {
 97     analysisManager->FillH1(1, fTotalEnergyDeposit);
 98   }
 99   if (sb[0] > 0) {
100     analysisManager->FillH1(2, sb[0]);
101   }
102   if (sb[1] > 0) {
103     analysisManager->FillH1(3, sb[1]);
104   }
105 }
106 
107 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
108 
109 void EventAction::ComputeStrandBreaks(G4int* sb)
110 {
111   // sb quantities
112   //
113   G4int ssb1 = 0;
114   G4int ssb2 = 0;
115   G4int dsb = 0;
116 
117   // nucleotide id and energy deposit for each strand
118   G4int nucl1;
119   G4int nucl2;
120   G4double edep1;
121   G4double edep2;
122 
123   // Read strand1
124   //
125   while (!fEdepStrand1.empty()) {
126     nucl1 = fEdepStrand1.begin()->first;
127     edep1 = fEdepStrand1.begin()->second;
128     fEdepStrand1.erase(fEdepStrand1.begin());
129 
130     // SSB in strand1
131     //
132     if (edep1 >= fThresEdepForSSB / eV) {
133       ssb1++;
134     }
135 
136     // Look at strand2
137     //
138     if (!fEdepStrand2.empty()) {
139       do {
140         nucl2 = fEdepStrand2.begin()->first;
141         edep2 = fEdepStrand2.begin()->second;
142         if (edep2 >= fThresEdepForSSB / eV) {
143           ssb2++;
144         }
145         fEdepStrand2.erase(fEdepStrand2.begin());
146       } while (((nucl1 - nucl2) > fThresDistForDSB) && (!fEdepStrand2.empty()));
147 
148       // no dsb
149       //
150       if (nucl2 - nucl1 > fThresDistForDSB) {
151         fEdepStrand2[nucl2] = edep2;
152         if (edep2 >= fThresEdepForSSB / eV) {
153           ssb2--;
154         }
155       }
156 
157       // one dsb
158       //
159       if (std::abs(nucl2 - nucl1) <= fThresDistForDSB) {
160         if ((edep2 >= fThresEdepForSSB / eV) && (edep1 >= fThresEdepForSSB / eV)) {
161           ssb1--;
162           ssb2--;
163           dsb++;
164         }
165       }
166     }
167   }
168 
169   // End with not processed data
170   //
171   while (!fEdepStrand1.empty()) {
172     nucl1 = fEdepStrand1.begin()->first;
173     edep1 = fEdepStrand1.begin()->second;
174     if (edep1 >= fThresEdepForSSB / eV) {
175       ssb1++;
176     }
177     fEdepStrand1.erase(fEdepStrand1.begin());
178   }
179 
180   while (!fEdepStrand2.empty()) {
181     nucl2 = fEdepStrand2.begin()->first;
182     edep2 = fEdepStrand2.begin()->second;
183     if (edep2 >= fThresEdepForSSB / eV) {
184       ssb2++;
185     }
186     fEdepStrand2.erase(fEdepStrand2.begin());
187   }
188 
189   sb[0] = ssb1 + ssb2;
190   sb[1] = dsb;
191 }
192