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Geant4/examples/extended/medical/dna/clustering/include/ClusteringAlgo.hh

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  1 //
  2 // ********************************************************************
  3 // * License and Disclaimer                                           *
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  9 // * include a list of copyright holders.                             *
 10 // *                                                                  *
 11 // * Neither the authors of this software system, nor their employing *
 12 // * institutes,nor the agencies providing financial support for this *
 13 // * work  make  any representation or  warranty, express or implied, *
 14 // * regarding  this  software system or assume any liability for its *
 15 // * use.  Please see the license in the file  LICENSE  and URL above *
 16 // * for the full disclaimer and the limitation of liability.         *
 17 // *                                                                  *
 18 // * This  code  implementation is the result of  the  scientific and *
 19 // * technical work of the GEANT4 collaboration.                      *
 20 // * By using,  copying,  modifying or  distributing the software (or *
 21 // * any work based  on the software)  you  agree  to acknowledge its *
 22 // * use  in  resulting  scientific  publications,  and indicate your *
 23 // * acceptance of all terms of the Geant4 Software license.          *
 24 // ********************************************************************
 25 //
 26 // This example is provided by the Geant4-DNA collaboration
 27 // Any report or published results obtained using the Geant4-DNA software
 28 // shall cite the following Geant4-DNA collaboration publication:
 29 // Med. Phys. 37 (2010) 4692-4708
 30 // The Geant4-DNA web site is available at http://geant4-dna.org
 31 //
 32 // Authors: Henri Payno and Yann Perrot
 33 //
 34 //
 35 /// \file ClusteringAlgo.hh
 36 /// \brief Definition of the ClustreringAlgo class
 37 
 38 #ifndef ClusteringAlgo_H
 39 #define ClusteringAlgo_H 1
 40 
 41 #include "ClusterSBPoints.hh"
 42 #include "SBPoint.hh"
 43 
 44 #include <map>
 45 
 46 class ClusteringAlgoMessenger;
 47 
 48 class ClusteringAlgo
 49 {
 50   public:
 51     ClusteringAlgo(G4double pEps, G4int pMinPts, G4double pSPointsProb, G4double pEMinDamage,
 52                    G4double pEMaxDamage);
 53     ~ClusteringAlgo();
 54 
 55     // Get Set methods
 56     G4double GetEps() { return fEps; };
 57     void SetEps(G4double val) { fEps = val; };
 58     G4int GetMinPts() { return fMinPts; };
 59     void SetMinPts(G4int val) { fMinPts = val; };
 60     G4double GetSPointsProb() { return fSPointsProb; };
 61     void SetSPointsProb(G4double val) { fSPointsProb = val; };
 62     G4double GetEMinDamage() { return fEMinDamage; };
 63     void SetEMinDamage(G4double val) { fEMinDamage = val; };
 64     G4double GetEMaxDamage() { return fEMaxDamage; };
 65     void SetEMaxDamage(G4double val) { fEMaxDamage = val; };
 66 
 67     // Register a damage (position, edep)
 68     void RegisterDamage(G4ThreeVector, G4double);
 69 
 70     // Clustering Algorithm
 71     std::map<G4int, G4int> RunClustering();
 72 
 73     // Clean all data structures
 74     void Purge();
 75 
 76     // Return the number of simple break
 77     G4int GetSSB() const;
 78     // Return the number of complex simple break
 79     G4int GetComplexSSB() const;
 80     // Return the number of double strand break
 81     G4int GetDSB() const;
 82     // Return a map representing cluster size distribution
 83     // first G4int : cluster size (1 = SSB)
 84     // second G4int : counts
 85     std::map<G4int, G4int> GetClusterSizeDistribution();
 86 
 87   private:
 88     // Functions to check if SB candidate
 89     G4bool IsInSensitiveArea();
 90     G4bool IsEdepSufficient(G4double);
 91     // Check if a SB point can be merged to a cluster, and do it
 92     bool FindCluster(SBPoint* pPt);
 93     // Check if two points can be merged
 94     bool AreOnTheSameCluster(G4ThreeVector, G4ThreeVector, G4double);
 95     // Merge clusters
 96     void MergeClusters();
 97     // Add SSB to clusters
 98     void IncludeUnassociatedPoints();
 99 
100     // Parameters to run clustering algorithm
101     G4double fEps;  // distance to merge SBPoints
102     G4int fMinPts;  // number of SBPoints to create a cluster
103     G4double fSPointsProb;  // probability for a point to be in the sensitive area
104     G4double fEMinDamage;  // min energy to create a damage
105     G4double fEMaxDamage;  // energy to have a probability to create a damage = 1
106 
107     // Data structure containing all SB points
108     std::vector<SBPoint*> fpSetOfPoints;
109     // Datya structure containing all clusters
110     std::vector<ClusterSBPoints*> fpClusters;
111     // ID of the next SB point
112     unsigned int fNextSBPointID;
113 
114     ClusteringAlgoMessenger* fpClustAlgoMessenger;
115 };
116 
117 #endif
118